MATRIX-ASSISTED LASER DESORPTION OF LARGE BIOMOLECULES WITH A TEA-CO2-LASER

被引：118

作者：

OVERBERG, A ^{[1
]}

KARAS, M ^{[1
]}

HILLENKAMP, F ^{[1
]}

机构：

[1] UNIV MUNSTER,INST NEUROSCI,W-4400 MUNSTER,GERMANY

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 03期

关键词：

D O I：

10.1002/rcm.1290050308

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Matrix-assisted desorption/ionization of large biomolecules with a TEA-CO2 laser with a wavelength of 10.6-mu-m is demonstrated. TEA-CO2 LDI mass spectra are almost identical to those obtained with the Er-YAG (2.94-mu-m) infra-red (IR) laser and very similar to UV-LDI spectra. Most of the matrices usable for Er-YAG IR-LDI have been tested at 10.6-mu-m with success, and the main features of IR-LDI e.g., the tendency towards the formation of higher charges is shown.

引用

页码：128 / 131

页数：4