SYNTHESIS AND CHEMISTRY OF A QUINONE METHIDE MODEL FOR ANTHRACYCLINE ANTITUMOR ANTIBIOTICS

被引：36

作者：

ANGLE, SR

YANG, WJ

机构：

[1] Department of Chemistry, University of California, Riverside, Riverside

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1990年 / 112卷 / 11期

关键词：

D O I：

10.1021/ja00167a060

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In an effort to understand the chemistry of anthracycline antitumor antibiotic, a simple stable o-quinone methide has been constructed and fully characterized. The reaction of the quinone methide with nucleophiles, including 2’,3’-isopropylideneadenosine has been examined. © 1990, American Chemical Society. All rights reserved.

引用

页码：4524 / 4528

页数：5

共 23 条

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