COMPLEMENT DEFICIENCY AND DISEASE

被引：245

作者：

MORGAN, BP ^{[1
]}

WALPORT, MJ ^{[1
]}

机构：

[1] HAMMERSMITH HOSP, ROYAL POSTGRAD MED SCH, DEPT MED, LONDON W12 0NN, ENGLAND

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 09期

关键词：

D O I：

10.1016/0167-5699(91)90003-C

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Complement deficiency is associated with an increased prevalence of pyogenic infections and immune complex disease. The spectrum o f disease in deficient individuals depends on the stage in the complement system at which the block in activation occurs. Here, Paul Morgan and Mark Walport review current knowledge of hereditary complement deficiencies in humans, emphasizing the importance of these 'experiments of nature' in defining the roles o f complement in vivo. © 1991.

引用

页码：301 / 306

页数：6

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