GASTROINTESTINAL INVOLVEMENT IN TUBEROUS SCLEROSIS - 2 CASE-REPORTS

被引:17
作者
HIZAWA, K [1 ]
IIDA, M [1 ]
MATSUMOTO, T [1 ]
TOMINAGA, M [1 ]
HIROTA, C [1 ]
YAO, T [1 ]
FUJISHIMA, M [1 ]
机构
[1] KYUSHU UNIV, FAC MED, DEPT PATHOL 2, FUKUOKA 812, JAPAN
关键词
GASTROINTESTINAL POLYPOSIS; TUBEROUS SCLEROSIS COMPLEX; COWDENS DISEASE; HAMARTOMA;
D O I
10.1097/00004836-199407000-00012
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Two patients with tuberous sclerosis had multiple semispherical polyps in the large intestine, predominantly in the rectosigmoid colon. These were hamartomas with an excess of smooth muscle fibers in the stroma. In addition, the 21-year-old man had multiple tiny protrusions in the esophagus and oral fibroepithelial polyps. In the 31-year-old woman, who had pulmonary lymphangiomyomatosis with positive estrogen and progesterone receptors, hamartomatous gastric polyps, colonic leiomyoma, and adenomatous rectal polyps were also identified. Our findings suggest that gastrointestinal polyposis may be one of the phenotypes of tuberous sclerosis complex, possibly linking this disease with other hereditary polyposis syndromes.
引用
收藏
页码:46 / 49
页数:4
相关论文
共 19 条
[1]  
ALBRECHT S, 1992, CANCER-AM CANCER SOC, V70, P869, DOI 10.1002/1097-0142(19920815)70:4<869::AID-CNCR2820700424>3.0.CO
[2]  
2-E
[3]   2 UNUSUAL TUMORS OF THE GASTROINTESTINAL-TRACT IN A PATIENT WITH TUBEROUS SCLEROSIS [J].
BYARD, RW ;
PHILLIPS, GE ;
DARDICK, I ;
ROBERTSON, E ;
CARTER, RF ;
BOURNE, AJ .
JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 1991, 27 (02) :116-119
[4]   COLORECTAL POLYPS IN COWDENS DISEASE (MULTIPLE HAMARTOMA SYNDROME) [J].
CARLSON, GJ ;
NIVATVONGS, S ;
SNOVER, DC .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1984, 8 (10) :763-770
[5]   COWDENS DISEASE - A CASE-REPORT AND LITERATURE-REVIEW [J].
CHEN, YM ;
OTT, DJ ;
WU, WC ;
GELFAND, DW .
GASTROINTESTINAL RADIOLOGY, 1987, 12 (04) :325-329
[6]  
COMDR LT, 1950, RADIOLOGY, V55, P522
[7]   COLONIC HAMARTOMAS IN TUBEROUS SCLEROSIS [J].
DEVROEDE, G ;
LEMIEUX, B ;
MASSE, S ;
LAMARCHE, J ;
HERMAN, PS .
GASTROENTEROLOGY, 1988, 94 (01) :182-188
[8]   TUBEROUS SCLEROSIS [J].
FRYER, AE .
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 1991, 84 (12) :699-701
[9]  
GOMEZ MR, 1991, ANN NY ACAD SCI, V615, P1
[10]  
GOULD SR, 1991, ANN NY ACAD SCI, V615, P71