DELTA-(L-ALPHA-AMINOADIPYL)-L-CYSTEINYL-D-VALINE SYNTHETASE (ACV SYNTHETASE) - A MULTIFUNCTIONAL ENZYME WITH BROAD SUBSTRATE-SPECIFICITY FOR THE SYNTHESIS OF PENICILLIN AND CEPHALOSPORIN PRECURSORS

被引：100

作者：

BANKO, G

DEMAIN, AL

WOLFE, S

机构：

[1] MIT,DEPT APPL BIOL SCI,FERMENTAT MICROBIOL LAB,CAMBRIDGE,MA 02139

[2] QUEENS UNIV,DEPT CHEM,KINGSTON K7L 3N6,ONTARIO,CANADA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1987年 / 109卷 / 09期

关键词：

D O I：

10.1021/ja00243a068

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：2858 / 2860

页数：3

共 44 条

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[35] LUBBE C, 1985, J ANTIBIOT, V38, P1792
[36] PURIFICATION OF ISOPENICILLIN-N SYNTHETASE
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[37] DISSOCIATION OF CEPHAMYCIN AND CLAVULANIC ACID BIOSYNTHESIS IN STREPTOMYCES-CLAVULIGERUS
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[38] ROSKOSKI R, 1970, BIOCHEMISTRY-US, V9, P4846
[39] ACCUMULATION OF TRIPEPTIDE DERIVATIVES BY MUTANTS OF CEPHALOSPORIUM-ACREMONIUM
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[J]. AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1979, 43 (01): : 155 - 160
[40] OXYGENATION OF [3-METHYL-H-3]DESACETOXYCEPHALOSPORIN-C [7-BETA-D-AMINOADIPAMIDO)-3-METHYLCEPH-3-EM-4-CARBOXYLIC ACID] TO [3-HYDROXYMETHYL-H-3]DESACETYLCEPHALOSPORIN-C BY 2-OXOGLUTARATE-LINKED DIOXYGENASES FROM ACREMONIUM-CHRYSOGENUM AND STREPTOMYCES-CLAVULIGERUS
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