SYNTHESIS AND ANTIINFLAMMATORY AND ANALGESIC ACTIVITY OF 5-AROYL-1,2-DIHYDRO-3H-PYRROLO[1,2-A]PYRROLE-1-CARBOXYLIC ACIDS AND RELATED-COMPOUNDS

被引：78

作者：

MUCHOWSKI, JM

UNGER, SH

ACKRELL, J

CHEUNG, P

COOPER, GF

COOK, J

GALLEGRA, P

HALPERN, O

KOEHLER, R

KLUGE, AF

VANHORN, AR

ANTONIO, Y

CARPIO, H

FRANCO, F

GALEAZZI, E

GARCIA, I

GREENHOUSE, R

GUZMAN, A

IRIARTE, J

LEON, A

PENA, A

PEREZ, V

VALDEZ, D

ACKERMAN, N

BALLARON, SA

MURTHY, DVK

ROVITO, JR

TOMOLONIS, AJ

YOUNG, JM

ROOKS, WH

机构：

[1] SYNTEX RES CORP,INST BIOL SCI,PALO ALTO,CA 94304

[2] SYNTEX SA,DIV INVEST,MEXICO CITY 10,MEXICO

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 08期

关键词：

D O I：

10.1021/jm00146a011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1037 / 1049

页数：13

共 39 条

[1] SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF 6,11-DIHYDRO-11-OXODIBENZO[B,E]THIEPINALKANOIC ACIDS AND RELATED COMPOUNDS [J].

ACKRELL, J ;

ANTONIO, Y ;

FRANCO, F ;

LANDEROS, R ;

LEON, A ;

MUCHOWSKI, JM ;

MADDOX, ML ;

NELSON, PH ;

ROOKS, WH ;

ROSZKOWSKI, AP ;

WALLACH, MB .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (10) :1035-1044

[2]

BERKOWITZ SS, 1974, CURR THER RES CLIN E, V16, P442

[3] SYNTHESIS OF 1,2-DIHYDRO-3H-PYRROLO[1,2-A]PYRROLE-1-CARBOXYLIC ACIDS AND HOMOLOGOUS PYRIDINE AND AZEPINE ANALOGS THEREOF [J].

CARPIO, H ;

GALEAZZI, E ;

GREENHOUSE, R ;

GUZMAN, A ;

VELARDE, E ;

ANTONIO, Y ;

FRANCO, F ;

LEON, A ;

PEREZ, V ;

SALAS, R ;

VALDES, D ;

ACKRELL, J ;

CHO, D ;

GALLEGRA, P ;

HALPERN, O ;

KOEHLER, R ;

MADDOX, ML ;

MUCHOWSKI, JM ;

PRINCE, A ;

TEGG, D ;

THURBER, TC ;

VANHORN, AR ;

WREN, D .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1982, 60 (18) :2295-2312

[4] 5-BENZOYL-1-METHYLPYRROLE-2-ACETIC ACIDS AS ANTIINFLAMMATORY AGENTS .2. 4-METHYL COMPOUNDS [J].

CARSON, JR ;

WONG, S .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (02) :172-174

[5] ACID-MEDIATED REARRANGEMENT OF ACYLPYRROLES [J].

CARSON, JR ;

DAVIS, NM .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (05) :839-843

[6] CONFIDENCE-INTERVAL ESTIMATORS FOR PARAMETERS ASSOCIATED WITH QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS [J].

DIETRICH, SW ;

DREYER, ND ;

HANSCH, C ;

BENTLEY, DL .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (11) :1201-1205

[7] ANTI-INFLAMMATORY 5,6-DIHYDRO-11-OXODIBENZ[B,E]AZEPINE-3-ACETIC ACIDS [J].

DUNN, JP ;

MUCHOWSKI, JM ;

NELSON, PH .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (09) :1097-1099

[8] DIBENZTROPONEACETIC AND DIBENZTROPROPIONIC ACIDS - POTENT NEW ANTIINFLAMMATORY AGENTS [J].

DUNN, JP ;

GREEN, DM ;

NELSON, PH ;

ROOKS, WH ;

TOMOLONIS, A ;

UNTCH, KG .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (12) :1557-1562

[9] MULTICOLLINEARITY IN REGRESSION ANALYSIS - PROBLEM REVISITED [J].

FARRAR, DE ;

GLAUBER, RR .

REVIEW OF ECONOMICS AND STATISTICS, 1967, 49 (01) :92-107

[10] QUANTITATIVE-DETERMINATION OF PROSTAGLANDINS AND MALONDIALDEHYDE FORMED BY ARACHIDONATE OXYGENASE (PROSTAGLANDIN SYNTHETASE) SYSTEM OF BOVINE SEMINAL VESICLE [J].

FLOWER, RJ ;

CUSHMAN, DW ;

CHEUNG, HS .

PROSTAGLANDINS, 1973, 4 (03) :325-341

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