ISOLATION AND SEQUENCING OF A CDNA-ENCODING THE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM TOXOPLASMA-GONDII

被引：8

作者：

VASANTHAKUMAR, G

VANGINKEL, S

PARISH, G

机构：

[1] Structural and Molecular Biology Group, Pharmaceutical Division, Southern Research Institute, Birmingham

来源：

GENE | 1994年 / 147卷 / 01期

关键词：

RECOMBINANT DNA; MOLECULAR CLONING; LAMBDA-ZAPII; COMPLEMENTATION; PATHOGEN; PURINE PATHWAY; HGPRT-DEFICIENT ESCHERICHIA COLI;

D O I：

10.1016/0378-1119(94)90058-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A hypoxanthine-guanine phosphoribosyltransferase-encoding gene (HGPRT) from Toxoplasma gondii has been isolated and sequenced. The identity of the enzyme was determined by sequence comparison and complementation in a mutant Escherichia coli.

引用

页码：153 / 154

页数：2

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