A COMPARATIVE-STUDY OF A PROGESTIN-ONLY ORAL-CONTRACEPTIVE VERSUS NONHORMONAL METHODS IN LACTATING WOMEN IN BUENOS-AIRES, ARGENTINA

被引:27
作者
MOGGIA, AV [1 ]
HARRIS, GS [1 ]
DUNSON, TR [1 ]
DIAZ, R [1 ]
MOGGIA, MS [1 ]
FERRER, MA [1 ]
MCMULLEN, SL [1 ]
机构
[1] FAMILY HLTH INT,RES TRIANGLE PK,NC 27709
关键词
D O I
10.1016/0010-7824(91)90104-N
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A non-randomized comparative clinical trial of the progestin-only oral contraceptive (POC), Ovrette (75 mcg norgestrel) (Wyeth), versus non-hormonal methods was conducted at two clinics in Buenos Aires, Argentina. The trial was designed to assess the breast feeding patterns of women choosing progestin-only oral contraception and non-hormonal methods of contraception, and to study the relationship between lactation and the clinical performance of a POC. Five-hundred women were allocated to either the progestin-only pill group (n = 250) or to the non-hormonal group (n = 250) and were followed up monthly for six months after admission. Measurements in mean infant weight, mean infant length, and mean head circumference were similar throughout the follow-up period. Non-hormonal users reported significantly more self-perceived decreases in milk production at the 5th and 6th month follow-up intervals. Acceptance and continued use of the pill were excellent, with only one woman discontinuing because of a pregnancy which was attributed to user failure. The principal side effect reported by women in both groups was intermenstrual bleeding.
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页码:31 / 43
页数:13
相关论文
共 15 条
[11]   D-NORGESTREL CONCENTRATIONS IN MATERNAL PLASMA, MILK, AND CHILD PLASMA DURING ADMINISTRATION OF ORAL-CONTRACEPTIVES TO NURSING WOMEN [J].
NILSSON, S ;
NYGREN, KG ;
JOHANSSON, EDB .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1977, 129 (02) :178-184
[12]  
Nilsson S, 1979, Res Reprod, V11, P1
[13]   LEVELS OF CONTRACEPTIVE STEROIDS IN BREAST-MILK AND PLASMA OF LACTATING WOMEN [J].
SAXENA, BN ;
SHRIMANKER, K ;
GRUDZINSKAS, JG .
CONTRACEPTION, 1977, 16 (06) :605-613
[14]   THE EFFECT OF DEPOT-MEDROXYPROGESTERONE ACETATE ON THE FETUS AND NURSING INFANT - A REVIEW [J].
SCHWALLIE, PC .
CONTRACEPTION, 1981, 23 (04) :375-386
[15]  
1984, CONTRACEPTION, V30, P505