THE 1ST ALKYLATION OF ORTHO-CARBORANES UNDER ESSENTIALLY NEUTRAL CONDITIONS - APPLICATION TO THE SYNTHESIS OF B-10 CARRIERS

被引：22

作者：

NEMOTO, H ^{[1
]}

RONG, F ^{[1
]}

YAMAMOTO, Y ^{[1
]}

机构：

[1] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 25期

关键词：

D O I：

10.1021/jo00312a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: The palladium-catalyzed reaction of 1,2-di-carbora-doso-dodecaboranes (o-carboranes) (1) with allyl ethyl carbonate (3) gave 2-allylated o-carboranes (2) in good to excellent yields. Compounds 2 could be converted to the corresponding diols (4), which were soluble in water and thus could be utilized as carriers for 10B neutron capture therapy. © 1990, American Chemical Society. All rights reserved.

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页码：6065 / 6066

页数：2

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