The molecular biology of SRY and its role in sex determination in mammals

被引：26

作者：

Koopman, P

机构：

[1] Centre for Molecular and Cellular Biology, The University of Queensland, Brisbane, QLD

来源：

REPRODUCTION FERTILITY AND DEVELOPMENT | 1995年 / 7卷 / 04期

关键词：

D O I：

10.1071/RD9950713

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

SRY is the gene that initiates the genetic cascade leading to testis development in mammals. Since its discovery in 1990 and the direct demonstration of its male-determining role in transgenic mice, attention has turned to understanding the biochemical mode of action of the SRY gene product, and to the identification of other genes in the sex-determining pathway. Recent progress in these efforts is summarized in this review.

引用

页码：713 / 722

页数：10

共 76 条

[1] VARIABLE TRANSFER OF Y-SPECIFIC SEQUENCES IN XX MALES
AFFARA, NA
FERGUSONSMITH, MA
TOLMIE, J
KWOK, K
MITCHELL, M
JAMIESON, D
COOKE, A
FLORENTIN, L
[J]. NUCLEIC ACIDS RESEARCH, 1986, 14 (13) : 5375 - 5387
[2] GENETIC-EVIDENCE EQUATING SRY AND THE TESTIS-DETERMINING FACTOR
BERTA, P
HAWKINS, JR
SINCLAIR, AH
TAYLOR, A
GRIFFITHS, BL
GOODFELLOW, PN
FELLOUS, M
[J]. NATURE, 1990, 348 (6300) : 448 - 450
[3] BURGOYNE PS, 1988, DEVELOPMENT, V102, P443
[4] CIRCULAR TRANSCRIPTS OF THE TESTIS-DETERMINING GENE SRY IN ADULT-MOUSE TESTIS
CAPEL, B
SWAIN, A
NICOLIS, S
HACKER, A
WALTER, M
KOOPMAN, P
GOODFELLOW, P
LOVELLBADGE, R
[J]. CELL, 1993, 73 (05) : 1019 - 1030
[5] MEIOSIS IN MAN
CHANDLEY, AC
[J]. TRENDS IN GENETICS, 1988, 4 (03) : 79 - 84
[6] THE HUMAN SRY TRANSCRIPT
CLEPET, C
SCHAFER, AJ
SINCLAIR, AH
PALMER, MS
LOVELLBADGE, R
GOODFELLOW, PN
[J]. HUMAN MOLECULAR GENETICS, 1993, 2 (12) : 2007 - 2012
[7] SRY PROTEIN ENHANCES TRANSCRIPTION OF FOS-RELATED ANTIGEN-1 PROMOTER CONSTRUCTS
COHEN, DR
SINCLAIR, AH
MCGOVERN, JD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (10) : 4372 - 4376
[8] POLYMORPHISM OF A CAG TRINUCLEOTIDE REPEAT WITHIN SRY CORRELATES WITH B6.Y-DOM SEX REVERSAL
COWARD, P
NAGAI, K
CHEN, DG
THOMAS, HD
NAGAMINE, CM
LAU, YFC
[J]. NATURE GENETICS, 1994, 6 (03) : 245 - 250
[9] AN SRY-RELATED GENE EXPRESSED DURING SPERMATOGENESIS IN THE MOUSE ENCODES A SEQUENCE-SPECIFIC DNA-BINDING PROTEIN
DENNY, P
SWIFT, S
CONNOR, F
ASHWORTH, A
[J]. EMBO JOURNAL, 1992, 11 (10) : 3705 - 3712
[10] A CONSERVED FAMILY OF GENES RELATED TO THE TESTIS DETERMINING GENE, SRY
DENNY, P
SWIFT, S
BRAND, N
DABHADE, N
BARTON, P
ASHWORTH, A
[J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (11) : 2887 - 2887

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