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HUMAN HERPESVIRUS-6 IN SALIVARY-GLANDS

被引：156
作者：
FOX, JD
BRIGGS, M
WARD, PA
TEDDER, RS
机构：
[1] Department of Medical Microbiology, University College, Middlesex School of Medicine, London, W1 P 7PN
来源：
LANCET | 1990年 / 336卷 / 8715期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/0140-6736(90)93392-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In an investigation of the role of saliva in the transmission of human herpesvirus 6 (HHV6) sections of salivary gland tissue were screened for HHV6-specific DNA by in-situ hybridisation and for HHV6-specific protein by immunohistochemical staining with monoclonal antibodies against the virus. All of nine submandibular glands and one of four parotid glands showed the presence of H HV6 genome and expressed protein by these techniques. The findings are consistent with transmission of HHV6 by saliva and suggest that salivary gland tissue is a site of replication of the virus and a potential site for HHV6 persistence. © 1990.
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页码：590 / 593
页数：4
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