CHIROSPECIFIC SYNTHESIS OF AMINO-ACIDS, AMINO ALDEHYDES AND AMINO-ALCOHOLS FROM D-GLUCOSAMINE HYDROCHLORIDE - A MULTIGRAM SYNTHESIS OF N-BOC-L-SERINAL

被引：22

作者：

GIANNIS, A

HENK, T

机构：

[1] Institut für Organische Chemie, Biochemie der Universität Bonn, 5300 Bonn 1

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)88778-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-tert.-butyloxycarbonyl-L-serinal 4 was readily prepared from D-glucosamine hydrochloride 1 in three steps. The versatile synthetic intermediate 4 is chemically and configurationally stable for prolonged time and reacts with various stabilized phosphorus ylides to produce the enantiomerically pure (ee < 95%) allylamino alcohols 6 in high yields. © 1990.

引用

页码：1253 / 1256

页数：4

共 26 条

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