TYROSINASE INHIBITORS FROM BOLIVIAN MEDICINAL-PLANTS

被引：56

作者：

KUBO, I

YOKOKAWA, Y

KINSTHORI, I

机构：

[1] Department of Environmental Science, Policy, and Management, University of California, Berkeley

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 05期

关键词：

D O I：

10.1021/np50119a013

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bioassay-guided fractionation monitored by mushroom tyrosinase (EC 1.14.18.1) activity, afforded six inhibitors from three Bolivian medicinal plants, Buddleia coriacea, Gnaphalium cheiranthifolium, and Scheelea princeps. These inhibitors, which are all known phenolic compounds, inhibited the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) mediated by a mushroom tyrosinase.

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页码：739 / 743

页数：5

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