APPLICATION OF REVERSE-DEPT POLARIZATION TRANSFER PULSE SEQUENCE TO STUDY THE METABOLISM OF CARBON-13-LABELED SUBSTRATES IN PERFUSED ORGANS BY H-1-NMR SPECTROSCOPY

被引：12

作者：

DESMOULIN, F

CONFORTGOUNY, S

MASSON, S

BERNARD, M

DODDRELL, DM

COZZONE, PJ

机构：

[1] FAC MED TIMONE,CTR RESONANCE MAGNET BIOL & MED,CNRS,URA 1186,27 BD JEAN MOULIN,F-13005 MARSEILLE,FRANCE

[2] UNIV QUEENSLAND,DEPT CHEM,ST LUCIA,QLD 4067,AUSTRALIA

来源：

MAGNETIC RESONANCE IN MEDICINE | 1990年 / 15卷 / 03期

关键词：

D O I：

10.1002/mrm.1910150311

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Metabolism of 13C‐enriched metabolites can be advantageously studied by reverse‐polarization transfer methods. In this work an improved reverse‐DEPT sequence has been applied for the first time on perfused organs in a 20‐mm probe. The metabolic fate of 99% enriched [ 2‐13C] acetate perfused in excised rat liver and heart has been documented. © 1990 Academic Press, Inc. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：456 / 461

页数：6