A COHORT STUDY OF FAT INTAKE AND RISK OF BREAST-CANCER

被引：152

作者：

HOWE, GR

FRIEDENREICH, CM

JAIN, M

MILLER, AB

机构：

[1] National Cancer Institute of Canada Epidemiology Unit, Faculty of Medicine. University of Toronto, Toronto, ON

[2] Department of Preventive Medicine and Biostatistics, Faculty of Medicine. University of Toronto, Toronto, ON

来源：

JOURNAL OF THE NATIONAL CANCER INSTITUTE | 1991年 / 83卷 / 05期

关键词：

D O I：

10.1093/jnci/83.5.336

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Between 1982 and 1987, 519 newly incident, histologically confirmed cases of breast cancer were identified in a cohort of 56 837 women enrolled in the Canadian National Breast Screening Study. These women had completed a dietary questionnaire before the occurrence of their breast cancer, and this has been used to estimate their intake of dietary fat and several other nutrients. There is evidence of a positive association between breast cancer and total fat intake, with a relative risk of 1.35 (95% confidence interval, 1.00-1.82) per 77 g per day, and some evidence of a dose-response relationship (P = .052).

引用

页码：336 / 340

页数：5

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