DETERMINATION OF PARTICLE CONCENTRATION IN LATEXES BY TURBIDIMETRY

被引：19

作者：

IRACHE, JM ^{[1
]}

DURRER, C ^{[1
]}

PONCHEL, G ^{[1
]}

DUCHENE, D ^{[1
]}

机构：

[1] UNIV PARIS SUD, CNRS,URA 1218,PHARM GALEN & BIOPHARM LAB, 5 RUE JEAN BAPTISTE CLEMENT, F-92296 CHATENAY MALABRY, FRANCE

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 90卷 / 03期

关键词：

LATEX; NANOPARTICLES; TURBIDIMETRY; GRAVIMETRY; POLY(STYRENE);

D O I：

10.1016/0378-5173(93)90203-R

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The capacities and limits of turbidimetry for determining the particle concentration in latexes were studied. The size dependence of the specific turbidity (tau/C) was demonstrated for monodisperse latexes with sizes between 114 and 1060 nm. The particle concentration (C) of different latexes was calculated from turbidity values. The observations were also valid for polydisperse systems and the comparison between turbidimetric and gravimetric concentrations showed similar results (p < 0.05). By turbidimetry the exact concentration of even very small samples could be determined in a non-destructive way.

引用

页码：R9 / R12

页数：4

共 11 条

[1] CHEESMAN GCN, 1978, PARTICLE SIZE ANAL, P160
[2] GOULARI E, 1987, PART CHARACT, V4, P96
[3] GUIOT P, 1986, POLYM NANOPARTICLES
[4] KOURTI T, 1991, ACS SYM SER, V472, P34
[5] KOURTI T, 1990, POLYM MATER SCI ENG, V62, P301
[6] PERORAL ADMINISTRATION OF NANOPARTICLES
KREUTER, J
[J]. ADVANCED DRUG DELIVERY REVIEWS, 1991, 7 (01) : 71 - 86
[7] ISOBUTYL CYANOACRYLATE NANOPARTICLES AS A SOLID-PHASE FOR AN EFFICIENT IMMUNORADIOMETRIC ASSAY
MANIL, L
ROBLOTTREUPEL, L
COUVREUR, P
[J]. BIOMATERIALS, 1986, 7 (03) : 212 - 216
[8] Articles on the optical characteristics of turbid tubes, especially colloidal metal solutions.
Mie, G
[J]. ANNALEN DER PHYSIK, 1908, 25 (03) : 377 - 445
[9] PARTICLE SIZE DISTRIBUTION IN RUBBER LATEX
WALES, M
[J]. JOURNAL OF PHYSICAL CHEMISTRY, 1962, 66 (10) : 1768 - &
[10] ESTIMATION OF PARTICLE-SIZE DISTRIBUTIONS FROM TURBIDIMETRIC MEASUREMENTS
YANG, KC
HOGG, R
[J]. ANALYTICAL CHEMISTRY, 1979, 51 (06) : 758 - 763

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