DETERMINATION OF PARTICLE CONCENTRATION IN LATEXES BY TURBIDIMETRY

被引：19

作者：

IRACHE, JM ^{[1
]}

DURRER, C ^{[1
]}

PONCHEL, G ^{[1
]}

DUCHENE, D ^{[1
]}

机构：

[1] UNIV PARIS SUD, CNRS,URA 1218,PHARM GALEN & BIOPHARM LAB, 5 RUE JEAN BAPTISTE CLEMENT, F-92296 CHATENAY MALABRY, FRANCE

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 90卷 / 03期

关键词：

LATEX; NANOPARTICLES; TURBIDIMETRY; GRAVIMETRY; POLY(STYRENE);

D O I：

10.1016/0378-5173(93)90203-R

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The capacities and limits of turbidimetry for determining the particle concentration in latexes were studied. The size dependence of the specific turbidity (tau/C) was demonstrated for monodisperse latexes with sizes between 114 and 1060 nm. The particle concentration (C) of different latexes was calculated from turbidity values. The observations were also valid for polydisperse systems and the comparison between turbidimetric and gravimetric concentrations showed similar results (p < 0.05). By turbidimetry the exact concentration of even very small samples could be determined in a non-destructive way.

引用

页码：R9 / R12

页数：4