A NOVEL ENTRY TO THE VITAMIN-D TRIENE SYSTEM

被引：12

作者：

MASCARENAS, JL ^{[1
]}

GARCIA, AM ^{[1
]}

CASTEDO, L ^{[1
]}

MOURINO, A ^{[1
]}

机构：

[1] UNIV SANTIAGO COMPOSTELA,SECC ALCALOIDES,E-15706 SANTIAGO,SPAIN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(00)60832-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of Negishi's cyclization methodology to the synthesis of (Z)-1-iodo-1,3-bis-exocyclic-dienes from acyclic precursors is described. This kind of compounds can be used for the preparation of conjugated systems such us the triene of vitamin D.

引用

页码：7589 / 7592

页数：4

共 41 条

[11] THE VITAMIN-D STORY - A COLLABORATIVE EFFORT OF BASIC SCIENCE AND CLINICAL MEDICINE
DELUCA, HF
[J]. FASEB JOURNAL, 1988, 2 (03) : 224 - 236
[12] LARGE RATE ACCELERATIONS IN THE STILLE REACTION WITH TRI-2-FURYLPHOSPHINE AND TRIPHENYLARSINE AS PALLADIUM LIGANDS - MECHANISTIC AND SYNTHETIC IMPLICATIONS
FARINA, V
KRISHNAN, B
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (25) : 9585 - 9595
[13] STUDIES OF VITAMIN-D (CALCIFEROL) AND ITS ANALOGS .39. AROCALCIFEROLS - SYNTHESIS AND BIOLOGICAL EVALUATION OF AROMATIC SIDE-CHAIN ANALOGS OF 1-ALPHA,25-DIHYDROXYVITAMIN-D3
FIGADERE, B
NORMAN, AW
HENRY, HL
KOEFFLER, HP
ZHOU, JY
OKAMURA, WH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (08) : 2452 - 2463
[14] PHAGOCYTIC-CELLS SYNTHESIZE 19-NOR-10-KETO-25-HYDROXYVITAMIN-D3, A METABOLITE THAT MAY INDUCE DIFFERENTIATION OF THE HUMAN MONOBLASTIC CELL-LINE U937
GRAY, TK
MILLINGTON, DS
MALTBY, DA
WILLIAMS, ME
COHEN, MS
DODD, RC
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (23) : 8218 - 8221
[15] EFFICIENT ENANTIOSPECIFIC SYNTHESIS OF KEY A-RING SYNTHONS FOR THE PREPARATION OF 1-ALPHA,25-DIHYDROXYVITAMIN-D3 USING A CHROMIUM(II)-MEDIATED REACTION
HATAKEYAMA, S
NUMATA, H
OSANAI, K
TAKANO, S
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (15) : 3515 - 3517
[16] STRUCTURES AND BIOLOGICAL-ACTIVITIES OF VITAMIN-D METABOLITES AND THEIR ANALOGS
IKEKAWA, N
[J]. MEDICINAL RESEARCH REVIEWS, 1987, 7 (03) : 333 - 366
[17] KIEGIEL J, 1991, TETRAHEDRON LETT, V32, P6057, DOI 10.1016/0040-4039(91)80752-R
[18] CALCIPOTRIOL (MC-903) - PHARMACOKINETICS IN RATS AND BIOLOGICAL-ACTIVITIES OF METABOLITES - A COMPARATIVE-STUDY WITH 1,25(OH)2D3
KISSMEYER, AM
BINDERUP, L
[J]. BIOCHEMICAL PHARMACOLOGY, 1991, 41 (11) : 1601 - 1606
[19] AN ENANTIOSELECTIVE SYNTHESIS OF THE A-RING SYNTHON FOR VITAMIN-D3 METABOLITES BY CHEMICOENZYMATIC APPROACH
KOBAYASHI, S
SHIBATA, J
SHIMADA, M
OHNO, M
[J]. TETRAHEDRON LETTERS, 1990, 31 (11) : 1577 - 1580
[20] HIGH-FIELD NMR-STUDIES ON VITAMINS AND PROSTAGLANDINS .4. A PROTON MAGNETIC-RESONANCE NUCLEAR OVERHAUSER ENHANCEMENT STUDY - APPLICATION TO VITAMIN-D DERIVATIVES D2 AND D3
KOTOVYCH, G
AARTS, GHM
BOCK, K
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1980, 58 (12): : 1206 - 1210

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