UPTAKE OF THE NEUROTOXIN 1-METHYL-4-PHENYLPYRIDINE (MPP+) BY MITOCHONDRIA AND ITS RELATION TO THE INHIBITION OF THE MITOCHONDRIAL OXIDATION OF NAD+-LINKED SUBSTRATES BY MPP+

被引：248

作者：

RAMSAY, RR

SALACH, JI

SINGER, TP

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM BIOPHYS,SAN FRANCISCO,CA 94143

[2] VET ADM MED CTR,DIV MOLEC BIOL,SAN FRANCISCO,CA 94121

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1986年 / 134卷 / 02期

关键词：

D O I：

10.1016/S0006-291X(86)80483-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：743 / 748

页数：6

共 12 条

[1] BERGMEYER HU, 1974, METHODS BIOCH ANAL, V2
[2] QUANTITATIVE CHARACTERISTICS OF GLUTAMATE TRANSPORT IN RAT-LIVER MITOCHONDRIA
BRADFORD, NM
MCGIVAN, JD
[J]. BIOCHEMICAL JOURNAL, 1973, 134 (04) : 1023 - 1029
[3] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE
CHIBA, K
TREVOR, A
CASTAGNOLI, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) : 574 - 578
[4] PARKINSONISM-INDUCING NEUROTOXIN, N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE - UPTAKE OF THE METABOLITE N-METHYL-4-PHENYLPYRIDINE BY DOPAMINE NEURONS EXPLAINS SELECTIVE TOXICITY
JAVITCH, JA
DAMATO, RJ
STRITTMATTER, SM
SNYDER, SH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (07) : 2173 - 2177
[5] INHIBITION OF NADH-LINKED OXIDATION IN BRAIN MITOCHONDRIA BY 1-METHYL-4-PHENYL-PYRIDINE, A METABOLITE OF THE NEUROTOXIN, 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE
NICKLAS, WJ
VYAS, I
HEIKKILA, RE
[J]. LIFE SCIENCES, 1985, 36 (26) : 2503 - 2508
[6] NICKLAS WJ, 1986, MPTP NEUROTOXIN PROD
[7] CORRELATION OF UNSPECIFIC PERMEABLE MITOCHONDRIAL SPACES WITH INTERMEMBRANE SPACES
PFAFF, E
KLINGENBERG, M
RITT, E
VOGELL, W
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1968, 5 (02): : 222 - +
[8] OXIDATION OF THE NEUROTOXIC AMINE 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) BY MONOAMINE OXIDASE-A AND OXIDASE-B AND SUICIDE INACTIVATION OF THE ENZYMES BY MPTP
SALACH, JI
SINGER, TP
CASTAGNOLI, N
TREVOR, A
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 125 (02) : 831 - 835
[9] ENZYMATIC PROPERTIES OF INNER AND OUTER MEMBRANES OF RAT LIVER MITOCHONDRIA
SCHNAITMAN, C
GREENAWALT, JW
[J]. JOURNAL OF CELL BIOLOGY, 1968, 38 (01) : 158 - +
[10] SHINKA T, UNPUB

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