EFFECTS OF RAPID EYE-MOVEMENT SLEEP-DEPRIVATION ON THE PROPERTIES OF STRIATAL DOPAMINERGIC SYSTEM

被引：17

作者：

HAMDI, A ^{[1
]}

BROCK, J ^{[1
]}

ROSS, K ^{[1
]}

PRASAD, C ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV,MED CTR,DEPT MED ENDOCRINOL,NEW ORLEANS,LA 70112

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1993年 / 46卷 / 04期

关键词：

RAPID EYE MOVEMENT SLEEP DEPRIVATION; RAT; DOPAMINE RECEPTORS; DOPAMINE UPTAKE SITES; STRIATUM;

D O I：

10.1016/0091-3057(93)90214-E

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Using the water tank procedure, we have examined the effects of rapid eye movement (REM) sleep deprivation and associated stress on the properties of striatal dopaminergic system. While stress decreased the number of D1 and D2 dopamine receptors, a combination of REM sleep deprivation attenuated the decrease. The ratio of D1 to D2 densities, however, increased on both the stress and REM sleep deprivation groups. In contrast, the number of dopamine uptake sites remained unchanged. The enhanced behavioral responses to dopaminergic stimulants after REM sleep deprivation are discussed.

引用

页码：863 / 866

页数：4

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