INTERFERON-GAMMA IN THE MANAGEMENT OF INFECTIOUS-DISEASES

被引：107

作者：

GALLIN, JI

FARBER, JM

HOLLAND, SM

NUTMAN, TB

机构：

[1] NIAID, CLIN INVEST LAB, BETHESDA, MD 20892 USA

[2] NIAID, HOST DEF LAB, BETHESDA, MD 20892 USA

[3] NIAID, PARASIT DIS LAB, BETHESDA, MD 20892 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1995年 / 123卷 / 03期

关键词：

D O I：

10.7326/0003-4819-123-3-199508010-00009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Interferon-gamma has pleiotropic adjuvant effects on host defenses. These effects have made interferon-gamma particularly useful for enhancing host defenses in patients with chronic granulomatous disease of childhood and thus for reducing the incidence of life-threatening infections in these patients. Increasingly, data suggest that interferon-gamma will be useful for treating infections characterized by intracellular persistence in macrophages, such as toxoplasmosis, leishmaniasis, and mycobacteriosis. Interferon-gamma is emerging as an important cytokine for use in the treatment of infectious diseases.

引用

页码：216 / 224

页数：9

共 63 条

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