USE OF VARIOUS MEASUREMENTS FOR BIOMASS ESTIMATION

被引：26

作者：

CHATTAWAY, T ^{[1
]}

DEMAIN, AL ^{[1
]}

STEPHANOPOULOS, G ^{[1
]}

机构：

[1] MIT,DEPT CHEM ENGN,CAMBRIDGE,MA 02139

来源：

BIOTECHNOLOGY PROGRESS | 1992年 / 8卷 / 01期

关键词：

D O I：

10.1021/bp00013a012

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Electron, carbon, and nitrogen balances can be thought of as relationships among the time rates of change of the various compounds participating in a fermentation process. As such, they define the minimum number of necessary measurements from which the remaining rates cari be determined through the use of the balances. All possibilities, however, are not equivalent, and some of them lead to singularities and solutions of high sensitivity. These possibilities are reviewed in this paper, and suggestions are offered in regard to the combination of rate measurements from which robust biomass estimates can be produced.

引用

收藏

页码：81 / 84

页数：4

相关论文

共 10 条

[1] MASS BALANCING - AN EFFECTIVE TOOL FOR FERMENTATION PROCESS OPTIMIZATION [J].

ACEVEDO, F .

CRC CRITICAL REVIEWS IN BIOTECHNOLOGY, 1987, 6 (04) :309-322

[2] AN ADAPTIVE STATE ESTIMATOR FOR DETECTING CONTAMINANTS IN BIOREACTORS [J].

CHATTAWAY, T ;

STEPHANOPOULOS, GN .

BIOTECHNOLOGY AND BIOENGINEERING, 1989, 34 (05) :647-659

[3] COMPUTER-AIDED MATERIAL BALANCING FOR PREDICTION OF FERMENTATION PARAMETERS [J].

COONEY, CL ;

WANG, HY ;

WANG, DIC .

BIOTECHNOLOGY AND BIOENGINEERING, 1977, 19 (01) :55-67

[4] APPLICATION OF MASS AND ENERGY-BALANCE REGULARITIES TO PRODUCT FORMATION [J].

ERICKSON, LE ;

SELGA, SE ;

VIESTURS, UE .

BIOTECHNOLOGY AND BIOENGINEERING, 1978, 20 (10) :1623-1638

[5] STUDIES ON ONLINE BIOREACTOR IDENTIFICATION .3. SENSITIVITY PROBLEMS WITH RESPIRATORY AND HEAT EVOLUTION MEASUREMENTS [J].

GROSZ, R ;

STEPHANOPOULOS, G ;

SAN, KY .

BIOTECHNOLOGY AND BIOENGINEERING, 1984, 26 (10) :1198-1208

[6] PRODUCTIVITY AND HEAT GENERATION OF FERMENTATION UNDER OXYGEN LIMITATION [J].

MINKEVICH, IG ;

EROSHIN, VK .

FOLIA MICROBIOLOGICA, 1973, 18 (05) :376-385

[7] APPLICATION OF MACROSCOPIC PRINCIPLES TO MICROBIAL-METABOLISM [J].

ROELS, JA .

BIOTECHNOLOGY AND BIOENGINEERING, 1980, 22 (12) :2457-2514

[8] APPLICATION OF MACROSCOPIC BALANCES TO THE IDENTIFICATION OF GROSS MEASUREMENT ERRORS [J].

WANG, NS ;

STEPHANOPOULOS, G .

BIOTECHNOLOGY AND BIOENGINEERING, 1983, 25 (09) :2177-2208

[9] PHENOL-HYPOCHLORITE REACTION FOR DETERMINATION OF AMMONIA [J].

WEATHERBURN, MW .

ANALYTICAL CHEMISTRY, 1967, 39 (08) :971-+

[10]

[No title captured]