N-ALKYLATION OF EXOGENOUS HEME ANALOGS CAUSED BY DRUGS IN ISOLATED HEPATOCYTES - STRUCTURAL ISOMERISM AND CHIRALITY OF THE RESULTING PORPHYRINS

被引：7

作者：

DEMATTEIS, F ^{[1
]}

HARVEY, C ^{[1
]}

MARTIN, SR ^{[1
]}

机构：

[1] NATL INST MED RES,DIV PHYS BIOCHEM,LONDON NW7 1AA,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1986年 / 238卷 / 01期

关键词：

D O I：

10.1042/bj2380263

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：263 / 268

页数：6

共 23 条

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[2] FUNCTIONAL RECONSTITUTION OF RAT-LIVER CYTOCHROME-P-450 WITH MESOHEMIN
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[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 121 (01) : 95 - 101
[3] CORREIA MA, 1979, J BIOL CHEM, V254, P15
[4] CORREIA MA, 1981, J BIOL CHEM, V256, P5466
[5] STUDIES ON THE INHIBITION OF FERROCHELATASE BY N-ALKYLATED DICARBOXYLIC PORPHYRINS - STERIC FACTORS INVOLVED AND EVIDENCE THAT THE INHIBITION IS REVERSIBLE
DEMATTEIS, F
GIBBS, AH
HARVEY, C
[J]. BIOCHEMICAL JOURNAL, 1985, 226 (02) : 537 - 544
[6] STRUCTURAL ISOMERISM AND CHIRALITY OF N-MONOSUBSTITUTED PROTOPORPHYRINS - POSSIBLE RELEVANCE TO BINDING OF N-METHYL PROTOPORPHYRIN BY FERROCHELATASE AND TO ORIENTATION OF HEME IN CYTOCHROME-P450
DEMATTEIS, F
JACKSON, AH
GIBBS, AH
RAO, KRN
ATTON, J
WEERASINGHE, S
HOLLANDS, C
[J]. FEBS LETTERS, 1982, 142 (01) : 44 - 48
[7] N-ALKYLATION OF THE HEME MOIETY OF CYTOCHROME-P-450 CAUSED BY SUBSTITUTED DIHYDROPYRIDINES - PREFERENTIAL ATTACK OF DIFFERENT PYRROLE NITROGEN-ATOMS AFTER INDUCTION OF VARIOUS CYTOCHROME-P-450 ISOENZYMES
DEMATTEIS, F
GIBBS, AH
HOLLANDS, C
[J]. BIOCHEMICAL JOURNAL, 1983, 211 (02) : 455 - 461
[8] INACTIVATION OF CYTOCHROME-P-450 AND PRODUCTION OF N-ALKYLATED PORPHYRINS CAUSED IN ISOLATED HEPATOCYTES BY SUBSTITUTED DIHYDROPYRIDINES - STRUCTURAL REQUIREMENTS FOR LOSS OF HEME AND ALKYLATION OF THE PYRROLE NITROGEN ATOM
DEMATTEIS, F
HOLLANDS, C
GIBBS, AH
DESA, N
RIZZARDINI, M
[J]. FEBS LETTERS, 1982, 145 (01) : 87 - 92
[9] DEMATTEIS F, 1962, BIOCHEM J, V83, P1
[10] DEMATTEIS F, 1985, MICROSOMES DRUG OXID, P265

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