ESCHERICHIA-COLI INTEGRATION HOST FACTOR STABILIZES BACTERIOPHAGE MU-REPRESSOR INTERACTIONS WITH OPERATOR DNA INVITRO

被引：30

作者：

ALAZARD, R

BETERMIER, M

CHANDLER, M

机构：

[1] Centre de Recherches en Biochimie et Génétique Cellulaires, Toulouse, F31062

来源：

MOLECULAR MICROBIOLOGY | 1992年 / 6卷 / 12期

关键词：

D O I：

10.1111/j.1365-2958.1992.tb00895.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Using gel retardation and DNase I protection techniques, we have demonstrated that the Escherichia coli integration host factor (IHF) stabilizes the interaction between Mu repressor and its cognate operator-binding sites in vitro. These results are discussed in terms of a model in which IHF may commit the phage to the lytic or lysogenic pathway depending on the occupancy of the operator sites by the repressor.

引用

页码：1707 / 1714

页数：8

共 37 条

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