MEMBRANE TRAFFIC WARDENS AND PROTEIN SECRETION IN GRAM-NEGATIVE BACTERIA

被引：281

作者：

SALMOND, GPC

REEVES, PJ

机构：

[1] Department of Biological Science, University of Warwick, Coventry

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1993年 / 18卷 / 01期

关键词：

D O I：

10.1016/0968-0004(93)90080-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent progress in the genetic analysis of protein secretion in diverse Gram-negative bacteria has revealed three major, highly conserved but functionally independent pathways that involve accessory apparatus proteins. Protein secretion via the Type I pathway is signal sequence-independent with no free periplasmic intermediate. Secretion by the Type II pathway is signal sequence-dependent and via the periplasm. Recent results also suggest that a third (Type III) secretory pathway exists in which protein secretion is signal sequence-independent.

引用

页码：7 / 12

页数：6

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[21] COMPONENTS OF THE PROTEIN-EXCRETION APPARATUS OF PSEUDOMONAS-AERUGINOSA ARE PROCESSED BY THE TYPE-IV PREPILIN PEPTIDASE [J].