EFFECTS OF THE PLANT FLAVONOID BAOHUOSIDE-1 ON CANCER-CELLS INVITRO

被引：13

作者：

LI, SY

TEH, BS

SEOW, WK

LI, F

THONG, YH

机构：

[1] UNIV QUEENSLAND,MATER CHILDRENS HOSP,DEPT CHILD HLTH,IMMUNOBIOL LAB,BRISBANE,QLD 4101,AUSTRALIA

[2] CHINESE ACAD MED SCI,INST MED BIOTECHNOL,BEIJING,PEOPLES R CHINA

[3] CHINESE ACAD MED SCI,INST MED PLANT DEV,BEIJING,PEOPLES R CHINA

来源：

CANCER LETTERS | 1990年 / 53卷 / 2-3期

关键词：

anti-tumor activity; Berberidaceae family; Epimedium davidii; plant flavanoids;

D O I：

10.1016/0304-3835(90)90211-F

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The novel plant flavonoid 3,5,7,-trihydroxy-4′-methoxyl-8′-prenylflavone-3-O-α-L-rhamnopranoxide (designated baohuoside-1) was shown to have cytotoxic and cytostatic effects on 6 cancer cell-lines, by means of microscopy, 51Cr-release and growth inhibition. The IC50 on the cells tested ranged from 2.8 to 7.5 μg/ml. At tumouricidal concentrations, inhibition of DNA and RNA synthesis, but not protein synthesis was observed. © 1990.

引用

页码：175 / 181

页数：7

共 17 条

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[17] [No title captured]

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