NEONATAL ALLOIMMUNE THROMBOCYTOPENIA CAUSED BY AN ANTIBODY TO THE BAKA ANTIGEN

被引:6
作者
EISEN, M
MOTUM, P
GIBSON, J
UHR, E
GETT, M
KRONENBERG, H
WYLIE, B
机构
[1] ROYAL PRINCE ALFRED HOSP,DEPT HEMATOL,MISSEDEN RD,CAMPERDOWN,NSW 2050,AUSTRALIA
[2] ROYAL PRINCE ALFRED HOSP,NEW S WALES RED CROSS BLOOD TRANSFUS SERV,DEPT HEMATOL,CAMPERDOWN,NSW 2050,AUSTRALIA
[3] KING GEORGE V MEM HOSP,JOHN SPENCE NURSERY,CAMPERDOWN,NSW 2050,AUSTRALIA
关键词
NEONATAL ALLOIMMUNE THROMBOCYTOPENIA; ANTIPLATELET ANTIBODIES; BAKA;
D O I
10.3109/00313029009086663
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A 31 year old woman was assessed following delivery of her second child affected by neonatal alloimmune thrombocytopenia (NAIT). Antiplatelet antibodies with specificity for Bak(a) were identified in the woman's serum and her platelets were typed as Bak(a) negative whilst her husband's were Bak(a) positive: Unlike the majority of reported anti-Bak(a) antibodies in the literature, this patient's serum contained no contaminating anti-HLA antibodies. This is the first report of NAIT caused by an anti-Bak(a) without co-existing anti-HLA antibodies. An anti-Bak(a) antibody has not previously been reported in Australia. The current status of this antigen system is reviewed.
引用
收藏
页码:203 / 205
页数:3
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