THE CLINICAL-APPLICATION OF SERIAL BONE MASS MEASUREMENTS

被引：23

作者：

ROSS, PD ^{[1
]}

DAVIS, JW ^{[1
]}

WASNICH, RD ^{[1
]}

VOGEL, JM ^{[1
]}

机构：

[1] UNIV CALIF DAVIS, SACRAMENTO MED CTR, SCH MED, SACRAMENTO, CA 95817 USA

来源：

BONE AND MINERAL | 1991年 / 12卷 / 03期

关键词：

BONE LOSS RATE; BONE MINERAL CONTENT; OSTEOPOROSIS; STATISTICAL METHOD;

D O I：

10.1016/0169-6009(91)90032-U

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although the short-term precision of various bone mineral content (BMC) measurements is known, questions about the clinical use of serial BMC measurements remain: how frequently should BMC be measured? When is it appropriate to calculate bone loss rates? How are estimates of loss rate interpreted? This paper discusses both biological and technical sources of uncertainty, and the estimation of confidence limits for measured bone loss rates. For many, possible most, patients, calculation of bone loss rate may not be necessary; however, repeated measures of BMC can still be useful for re-evaluating fracture risk. Indications for repeating BMC measurements may include low initial BMC (moderate to high fracture risk), anticipation of rapid bone loss (e.g., menopause, estrogen discontinuation), and verification of treatment efficacy.

引用

页码：189 / 199

页数：11