NOSOCOMIAL LEGIONNAIRES-DISEASE - LESSONS FROM A 4-YEAR PROSPECTIVE-STUDY

被引：36

作者：

MARRIE, TJ

MACDONALD, S

CLARKE, K

HALDANE, D

机构：

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 1991年 / 19卷 / 02期

关键词：

D O I：

10.1016/0196-6553(91)90043-C

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We studied all cases of nosocomial pneumonia at our 800-bed tertiary care hospital from September 1983 to September 1987. Of the 813 cases of nosocomial pneumonia, 31 (3.8%) were definite (isolation of organism or fourfold rise in titer) and 21 (2.5%) were possible cases (single or stable antibody titer of greater-than-or-equal-to 1:256) of legionnaires' disease. The definite cases involved a more severe form of pneumonia and a significantly higher mortality rate-64% versus 14% (p < 0.0009) compared with the possible cases. Despite attempted comprehensive surveillance, only four (13%) of the definite cases of legionnaires' disease were found that would not have been diagnosed if the study were not ongoing. The yield from adequate (4- to 6-week convalescent serum samples) serologic testing was 5%, whereas the yield from sputum culture was 11%. We conclude that targeted surveillance of immunosuppressed patients with nosocomial pneumonia by culture of respiratory tract secretions for Legionella pneumophila is adequate for monitoring for the presence of legionnaires' disease in a hospital.

引用

页码：79 / 85

页数：7

共 26 条

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