DEVELOPMENT OF A THERMAL MICRO-BIOSENSOR FABRICATED ON A SILICON CHIP

被引：36

作者：

XIE, B ^{[1
]}

DANIELSSON, B ^{[1
]}

NORBERG, P ^{[1
]}

WINQUIST, F ^{[1
]}

LUNDSTROM, I ^{[1
]}

机构：

[1] LINKOPING UNIV,APPL PHYS LAB,S-58183 LINKOPING,SWEDEN

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1992年 / 6卷 / 1-3期

关键词：

D O I：

10.1016/0925-4005(92)80043-W

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the conventional enzyme thermistor (ET) when identical sample volumes (20-mu-l) were applied. Finally, future prospects in this field are discussed.

引用

页码：127 / 130

页数：4

共 6 条

[1] CALORIMETRIC BIOSENSORS [J].