CHARACTERIZATION OF THE CDNA AND 3 PROCESSED PSEUDOGENES FROM THE MURINE PROTEIN-KINASE CK2 ALPHA-SUBUNIT

被引：6

作者：

HOFFMANN, U ^{[1
]}

HECHT, R ^{[1
]}

BOLDYREFF, B ^{[1
]}

ISSINGER, OG ^{[1
]}

机构：

[1] UNIV SAARLAND,FR HUMANGENET,D-66421 HOMBURG,GERMANY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期

关键词：

PROTEIN KINASE CK2 ALPHA SUBUNIT; PROCESSED PSEUDOGENE; CDNA; (MOUSE);

D O I：

10.1016/0167-4781(94)00243-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Seven protein kinase CK2 alpha clones were isolated from a murine genomic DNA library. They were assigned to four different genomic loci (A,B,C,D). Locus D was previously identified as a processed pseudogene (Boldyreff et al. (1992) Biochem. Biophys. Res. Commun. 186, 723-730). Here we present sequences of genomic loci B and C and the murine CK2 alpha cDNA. Loci B and C are like locus D processed pseudogenes, however, with considerable differences among each other and to the cDNA, especially with respect to the lengths of the putative gene products. Genomic locus D would code for a protein of 82 amino acids, locus B for a protein of 132 amino acids and locus C product for the full length product of 391 amino acids as the murine cDNA.

引用

页码：337 / 340

页数：4

共 16 条

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