Vaccines for gonorrhea: Where are we on the curve?

被引：17

作者：

Blake, MS

Wetzler, LM

机构：

[1] UNIV IOWA, COLL MED, DEPT MICROBIOL, IOWA CITY, IA 52242 USA

[2] BOSTON UNIV, SCH MED, BOSTON CITY HOSP, MAXWELL FINLAND LAB INFECT DIS, BOSTON, MA 02118 USA

来源：

TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 12期

关键词：

D O I：

10.1016/S0966-842X(00)89012-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human antibodies that bind the gonococcal outer membrane modulate gonorrheal transmission and disease. The effects of antibody binding can favor either the host or the bacteria, and depend on the antigen involved. An effective gonococcal vaccine is feasible, but only by the careful selection and formulation of gonococcal antigens that elicit only host-protective antibodies.

引用

收藏

页码：469 / 474

页数：6

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