HPLC DETERMINATION OF CHLORAMPHENICOL AND THIAMPHENICOL RESIDUES IN GAMEBIRD MEATS

被引：10

作者：

DIPIETRA, AM ^{[1
]}

PIAZZA, V ^{[1
]}

ANDRISANO, V ^{[1
]}

CAVRINI, V ^{[1
]}

机构：

[1] UNIV BOLOGNA,INST AVIAN PATHOL,I-40064 OZZANO EMILIA,ITALY

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1995年 / 18卷 / 17期

关键词：

D O I：

10.1080/10826079508010468

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Liquid chromatographic methods for the determination of chloramphenicol (CAP) and thiamphenicol (TAP) residues in gamebird (pheasant, mallard and quail) meats were developed. The drugs were extracted from the homogenised tissues (muscle and liver) by water and the extracts were purified by subsequent partitions with Chem Elut CE 1020 cartridge - ethyl acetate and water - toluene. The recoveries were 67% for CAP and 72% for TAP. Chromatographic separations were performed on a Hypersil C-18 column and the peak identification and quantitation was made with a photodiode array detector. Using the first derivative of the chromatographic peak the selectivity of the analysis was improved. The elimination kinetics of CAP and TAP from the quail tissues were also evaluated.

引用

页码：3529 / 3543

页数：15

共 27 条

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