A NEW P-31 NMR METHOD FOR THE ENANTIOMERIC EXCESS DETERMINATION OF ALCOHOLS, AMINES AND AMINO-ACID ESTERS

被引：23

作者：

HULST, R

ZIJLSTRA, RWJ

FERINGA, BL

DEVRIES, NK

TENHOEVE, W

WYNBERG, H

机构：

[1] DSM RES & PATENTS,DEPT PHYS & ANALYT CHEM,GELEEN,NETHERLANDS

[2] SYNCOM BV,9747 AG GRONINGEN,NETHERLANDS

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(00)91790-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereoisomeric ester and amide derivatives of phosphoric acid chloride 2 show well separated signals in the P-31 NMR spectra allowing accurate e.e. determination of chiral alcohols, esters of amino acids and amines.

引用

页码：1339 / 1342

页数：4

共 22 条

[11] NMR DETERMINATION OF ENANTIOMERIC PURITY [J].

PARKER, D .

CHEMICAL REVIEWS, 1991, 91 (07) :1441-1457

[12]

PIRKLE WH, 1983, ASYMMETRIC SYNTHESIS, V1, pCH6

[13] QUININE - AN INEXPENSIVE CHIRAL SOLVATING AGENT FOR THE DETERMINATION OF ENANTIOMERIC COMPOSITION OF BINAPHTHYL DERIVATIVES AND ALKYLARYLCARBINOLS BY NMR-SPECTROSCOPY [J].

ROSINI, C ;

UCCELLOBARRETTA, G ;

PINI, D ;

ABETE, C ;

SALVADORI, P .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (19) :4579-4581

[14] GAS-CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS ON OPTICALLY-ACTIVE METAL-COMPLEX-FREE STATIONARY PHASES .2. GAS-CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS ON CYCLODEXTRIN DERIVATIVES [J].

SCHURIG, V ;

NOWOTNY, HP .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1990, 29 (09) :939-957

[15]

SCHURIG V, 1983, ASYMMETRIC SYNTHESIS, V1, pCH5

[16]

Seebach D., 1986, MODERN SYNTHETIC MET, V4, P125

[17] CHIRAL PURITY DETERMINATION BY H-1-NMR SPECTROSCOPY - NOVEL USE OF 1,1'-BINAPHTHYL-2,2'-DIYLPHOSPHORIC ACID [J].

SHAPIRO, MJ ;

ARCHINAL, AE ;

JAREMA, MA .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (24) :5826-5828

[18] QUANTITATIVE DETECTION OF REMOTELY DISPOSED CHIRAL CENTERS USING SE-77 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY [J].

SILKS, LA ;

DUNLAP, RB ;

ODOM, JD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (12) :4979-4982

[19] METHYLPHOSPHONIC DICHLORIDE AS REAGENT FOR THE DETERMINATION OF THE ENANTIOMERIC EXCESS OF CHIRAL THIOLS - SCOPE AND LIMITATIONS [J].

STRIJTVEEN, B ;

FERINGA, BL ;

KELLOGG, RM .

TETRAHEDRON, 1987, 43 (01) :123-130

[20] THE DESIGN OF RESOLVING AGENTS - CHIRAL CYCLIC PHOSPHORIC-ACIDS [J].

TENHOEVE, W ;

WYNBERG, H .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (23) :4508-4514

← 1 2 3 →