REAL-TIME OBSERVATION OF LOW-TEMPERATURE PROTEIN MOTIONS

被引：61

作者：

LEESON, DT ^{[1
]}

WIERSMA, DA ^{[1
]}

机构：

[1] UNIV GRONINGEN,CTR MAT SCI,9747 AG GRONINGEN,NETHERLANDS

来源：

PHYSICAL REVIEW LETTERS | 1995年 / 74卷 / 11期

关键词：

D O I：

10.1103/PhysRevLett.74.2138

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Optical methods were used to study the internal motions of myoglobin and cytochrome c. The experiments show that these proteins exhibit conformational fluctuations at temperatures as low as 2 K. The distribution of fluctuation rates can be measured in real time and turns out to be very sharp. The temperature dependence of the structural relaxation of myoglobin follows a simple Arrhenius law. The results are in agreement with existing models for protein dynamics. © 1995 The American Physical Society.

引用

页码：2138 / 2141

页数：4