TERNARY COMPLEX FACTORS - GROWTH-FACTOR REGULATED TRANSCRIPTIONAL ACTIVATORS

被引：642

作者：

TREISMAN, R

机构：

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 01期

关键词：

D O I：

10.1016/0959-437X(94)90097-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of a family of Ets domain proteins, the ternary complex factors (TCFs), are recruited to the c-fos serum response element by interaction with the serum response factor. Recent findings indicate that phosphorylation of TCFs occurs in response to activation of the MAP kinase pathway, and that regulation of TCF activity is an important mechanism by which the serum response element responds to growth factor signals.

引用

收藏

页码：96 / 101

页数：6

相关论文

共 43 条

[1]

ALVAREZ E, 1991, J BIOL CHEM, V266, P15277

[2]

BHATTACHARYA G, 1993, ONCOGENE, V8, P3459

[3] CHARACTERIZATION OF SAP-1, A PROTEIN RECRUITED BY SERUM RESPONSE FACTOR TO THE C-FOS SERUM RESPONSE ELEMENT [J].

DALTON, S ;

TREISMAN, R .

CELL, 1992, 68 (03) :597-612

[4] TRANSCRIPTION FACTOR P91 INTERACTS WITH THE EPIDERMAL GROWTH-FACTOR RECEPTOR AND MEDIATES ACTIVATION OF THE C-FOS GENE PROMOTER [J].

FU, XY ;

ZHANG, JJ .

CELL, 1993, 74 (06) :1135-1145

[5] PHOSPHORYLATION OF TRANSCRIPTION FACTOR P62TCF BY MAP KINASE STIMULATES TERNARY COMPLEX-FORMATION AT C-FOS PROMOTER [J].

GILLE, H ;

SHARROCKS, AD ;

SHAW, PE .

NATURE, 1992, 358 (6385) :414-417

[6] THE C-FOS SERUM RESPONSE ELEMENT RESPONDS TO PROTEIN KINASE-C-DEPENDENT AND KINASE-C-INDEPENDENT SIGNALS BUT NOT TO CYCLIC-AMP [J].

GILMAN, MZ .

GENES & DEVELOPMENT, 1988, 2 (04) :394-402

[7] DISTINCT PROTEIN TARGETS FOR SIGNALS ACTING AT THE C-FOS SERUM RESPONSE ELEMENT [J].

GRAHAM, R ;

GILMAN, M .

SCIENCE, 1991, 251 (4990) :189-192

[8] INDUCIBLE BINDING OF A FACTOR TO THE C-FOS REGULATORY REGION [J].

HAYES, TE ;

KITCHEN, AM ;

COCHRAN, BH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (05) :1272-1276

[9] OCCUPATION OF THE C-FOS SERUM RESPONSE ELEMENT INVIVO BY A MULTI-PROTEIN COMPLEX IS UNALTERED BY GROWTH-FACTOR INDUCTION [J].

HERRERA, RE ;

SHAW, PE ;

NORDHEIM, A .

NATURE, 1989, 340 (6228) :68-70

[10] IDENTIFICATION OF AN ONCOPROTEIN-RESPONSIVE AND UV-RESPONSIVE PROTEIN-KINASE THAT BINDS AND POTENTIATES THE C-JUN ACTIVATION DOMAIN [J].

HIBI, M ;

LIN, AN ;

SMEAL, T ;

MINDEN, A ;

KARIN, M .

GENES & DEVELOPMENT, 1993, 7 (11) :2135-2148

← 1 2 3 4 5 →