TERNARY COMPLEX FACTORS - GROWTH-FACTOR REGULATED TRANSCRIPTIONAL ACTIVATORS

被引：642

作者：

TREISMAN, R

机构：

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 01期

关键词：

D O I：

10.1016/0959-437X(94)90097-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of a family of Ets domain proteins, the ternary complex factors (TCFs), are recruited to the c-fos serum response element by interaction with the serum response factor. Recent findings indicate that phosphorylation of TCFs occurs in response to activation of the MAP kinase pathway, and that regulation of TCF activity is an important mechanism by which the serum response element responds to growth factor signals.

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页码：96 / 101

页数：6

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