CHEMICAL-STRUCTURE OF GLYCOSPHINGOLIPIDS ISOLATED FROM SPHINGOMONAS-PAUCIMOBILIS

被引：124

作者：

KAWAHARA, K ^{[1
]}

SEYDEL, U ^{[1
]}

MATSUURA, M ^{[1
]}

DANBARA, H ^{[1
]}

RIETSCHEL, ET ^{[1
]}

ZAHRINGER, U ^{[1
]}

机构：

[1] FORSCHUNGSINST BORSTEL,INST EXPTL BIOL & MED,W-2061 BORSTEL,GERMANY

来源：

FEBS LETTERS | 1991年 / 292卷 / 1-2期

关键词：

CHEMICAL STRUCTURE; GLYCOSPHINGOLIPID; DIHYDROSPHINGOSINE; LIPOPOLYSACCHARIDE; SPHINGOMONAS-PAUCIMOBILIS;

D O I：

10.1016/0014-5793(91)80845-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two novel glycosphingolipids were isolated from Sphingomonas paucimobilis and their structures were completely elucidated. The glycosyl portion of the glycosphingolipid consists of an alpha-D-Manp-[1 --> 2)alpha-D-Galp-(1 --> 6)-alpha-D-GlcpN-(1 -->4)-alpha-D-GlcpA-R tetrasaccharide. The hydrophobic residue R was found to be heterogeneous with respect to the dihydrosphingosine residue. Erythro-1,3-dihydroxy-2-amino-octadecane and erythro-1,3-dihydroxy-2-amino-cis-13,14-methyleneoctadecane were identified in comparable amounts. Both dihydrosphingosine derivatives were quantitatively substituted by an (S)-2-hydroxymyristic acid in amide linkage.

引用

页码：107 / 110

页数：4

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