CYTOCHROME-C OXIDASES - POLYPEPTIDE COMPOSITION, ROLE OF SUBUNITS, AND LOCATION OF ACTIVE METAL CENTERS

被引：29

作者：

AZZI, A

MULLER, M

机构：

[1] Institut für Biochemie und Molekularbiologie, Universität Bern, CH-3012 Bern

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1990年 / 280卷 / 02期

关键词：

D O I：

10.1016/0003-9861(90)90326-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The general structure of the enzyme, its polypeptide composition, and a proposal for a rational nomenclature are discussed. The mitochondrially coded and bacterial cytochrome c oxidase subunits have been analyzed with more attention focused on elucidating the number of metals present in the enzyme and the ligands available for their coordination. The picture of a 2 Cu/ 2 Fe enzyme has been compared with that of a 3 Cu/2 Fe enzyme and a new model is proposed for the location of the metal centers in the enzyme. © 1990.

引用

页码：242 / 251

页数：10

共 101 条

[11]

BISSON R, 1986, J BIOL CHEM, V261, P4373

[12]

BISSON R, 1978, J BIOL CHEM, V253, P1874

[13]

BISSON R, 1978, FRONTIERS BIOL ENERG, V2, P809

[14] ANALYSIS OF THE CU, FE, AND ZN CONTENTS IN CYTOCHROME-C OXIDASES FROM DIFFERENT SPECIES AND TISSUES BY PROTON-INDUCED X-RAY-EMISSION (PIXE) [J].