GROWTH-FACTORS - REGULATION OF NORMAL AND NEOPLASTIC GROWTH

被引：80

作者：

PUSZTAI, L

LEWIS, CE

LORENZEN, J

MCGEE, JO

机构：

[1] University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, Oxford, OX3 9DU, Academic Block

来源：

JOURNAL OF PATHOLOGY | 1993年 / 169卷 / 02期

关键词：

GROWTH FACTORS; NEOPLASIA; CARCINOGENESIS;

D O I：

10.1002/path.1711690204

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.

引用

页码：191 / 201

页数：11

共 79 条

[1] COMPLEXITY OF THE EARLY GENETIC RESPONSE TO GROWTH-FACTORS IN MOUSE FIBROBLASTS [J].

ALMENDRAL, JM ;

SOMMER, D ;

MACDONALDBRAVO, H ;

BURCKHARDT, J ;

PERERA, J ;

BRAVO, R .

MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (05) :2140-2148

[2] CHEMICAL CARCINOGENESIS - TOO MANY RODENT CARCINOGENS [J].

AMES, BN ;

GOLD, LS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (19) :7772-7776

[3]

AVIVI A, 1991, ONCOGENE, V6, P1089

[4]

BALKWILL FR, 1989, CYTOKINES CANCER THE, P182

[5] THE CELL BIOLOGY OF TRANSFORMING GROWTH-FACTOR-BETA [J].

BARNARD, JA ;

LYONS, RM ;

MOSES, HL .

BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1032 (01) :79-87

[6] HUMAN GLIOBLASTOMA CELL DERIVED TRANSFORMING GROWTH-FACTOR-BETA-2 - EVIDENCE FOR SECRETION OF BOTH HIGH AND LOW-MOLECULAR-WEIGHT BIOLOGICALLY-ACTIVE FORMS [J].

BODMER, S ;

HUBER, D ;

HEID, I ;

FONTANA, A .

JOURNAL OF NEUROIMMUNOLOGY, 1991, 34 (01) :33-42

[7] IDENTIFICATION OF THE HEPATOCYTE GROWTH-FACTOR RECEPTOR AS THE C-MET PROTOONCOGENE PRODUCT [J].

BOTTARO, DP ;

RUBIN, JS ;

FALETTO, DL ;

CHAN, AML ;

KMIECIK, TE ;

VANDEWOUDE, GF ;

AARONSON, SA .

SCIENCE, 1991, 251 (4995) :802-804

[8] TRANSMEMBRANE TGF-ALPHA PRECURSORS ACTIVATE EGF TGF-ALPHA RECEPTORS [J].

BRACHMANN, R ;

LINDQUIST, PB ;

NAGASHIMA, M ;

KOHR, W ;

LIPARI, T ;

NAPIER, M ;

DERYNCK, R .

CELL, 1989, 56 (04) :691-700

[9] THE HEPARIN-BINDING (FIBROBLAST) GROWTH-FACTOR FAMILY OF PROTEINS [J].

BURGESS, WH ;

MACIAG, T .

ANNUAL REVIEW OF BIOCHEMISTRY, 1989, 58 :575-606

[10] Oncogenes and anti-oncogenes [J].

Cooper, J. A. .

CURRENT OPINION IN CELL BIOLOGY, 1990, 2 (02) :285-295

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