PILOT-SCALE PRODUCTION OF L-PHENYLALANINE FROM D-GLUCOSE

被引：5

作者：

GIL, GH ^{[1
]}

KIM, SR ^{[1
]}

BAE, JC ^{[1
]}

LEE, JH ^{[1
]}

机构：

[1] CHEIL SUGAR & CO LTD,RES & DEV CTR,522-1 DOKPYONG RI,KYONGGI DO,SOUTH KOREA

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1985年 / 7卷 / 08期

关键词：

BACTERIOLOGY - Coliforms - CHEMICAL REACTIONS - Fermentation - SUGAR;

D O I：

10.1016/0141-0229(85)90124-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Effects of inoculum size and total sugar content on both L-phenylalanine productivity and titre have been investigated using a tyrosine auxotrophic regulatory mutant of Escherichia coli. Fermentations were carried out in a 500 litre pilot fermenter with intermittent feeding of D-glucose plus phosphate. It was found that the productivity was not greatly affected by inoculum size. However, the L-phenylalanine titre was significantly affected by total sugar content.

引用

页码：370 / 372

页数：3

共 7 条

[1]

AKASHI K, 1979, J FERMENT TECHNOL, V57, P321

[2] CONTINUOUS PRODUCTION OF PHENYLALANINE USING AN ESCHERICHIA-COLI REGULATORY MUTANT [J].

CHOI, YJ ;

TRIBE, DE .

BIOTECHNOLOGY LETTERS, 1982, 4 (04) :223-228

[3]

HONG KT, 1984, J FERMENT TECHNOL, V62, P49

[4]

HWANG SO, 1985, APPL MICROBIOL BIOTE

[5]

Park S. H., 1984, KOREAN J CHEM ENG, V1, P65

[6] ONLINE ESTIMATION OF CELL-GROWTH FOR GLUTAMIC-ACID FERMENTATION SYSTEM [J].

PARK, SH ;

HONG, KT ;

LEE, JH ;

BAE, JC .

EUROPEAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1983, 17 (03) :168-172

[7] MICROBIAL PRODUCTION OF L-PHENYLALANINE FROM N-ALKANES [J].

TOKORO, Y ;

OSHIMA, K ;

OKII, M ;

YAMAGUCHI, K ;

TANAKA, K ;

KINOSHITA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1970, 34 (10) :1516-+

← 1 →