A SYNTHESIS OF SUBSTITUTED 2-PYRONES BY CARBONYLATIVE CROSS-COUPLING-THERMOLYSIS OF 4-HALOCYCLOBUTENONES WITH ALKENYLSTANNANE, ARYLSTANNANE, AND HETEROARYLSTANNANE

被引：42

作者：

LIEBESKIND, LS

WANG, JY

机构：

[1] Department of Chemistry, Emory University Atlanta

来源：

TETRAHEDRON | 1993年 / 49卷 / 25期

关键词：

D O I：

10.1016/S0040-4020(01)87262-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium catalyzed carbonylative cross-coupling of 4-chloro-2,3-disubstituted-2-cyclobutenones with alkenyl-, aryl-, and heteroaryltin reagents and thermolysis provides a general method for the synthesis of 2,3,6-trisubstituted-2-pyrones. The reaction is regiospecific, coupling occurring preferentially at the 4-position of the cyclobutenone.

引用

收藏

页码：5461 / 5470

页数：10

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