STUDIES ON THE INHIBITION OF MITOCHONDRIAL-DNA REPLICATION BY 3'-AZIDO-3'-DEOXYTHYMIDINE AND OTHER DIDEOXYNUCLEOSIDE ANALOGS WHICH INHIBIT HIV-1 REPLICATION

被引：183

作者：

SIMPSON, MV ^{[1
]}

CHIN, CD ^{[1
]}

KEILBAUGH, SA ^{[1
]}

LIN, TS ^{[1
]}

PRUSOFF, WH ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

来源：

BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 07期

关键词：

D O I：

10.1016/0006-2952(89)90245-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1033 / 1036

页数：4

共 31 条

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[2] BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO
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[3] POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE
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[4] BALZARINI J, 1987, MOL PHARMACOL, V32, P162
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[6] DNA CHAIN TERMINATION BY 2',3'-DIDEOXYTHYMIDINE IN REPLICATING MAMMALIAN-CELLS
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[9] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) : 185 - 191
[10] PHOSPHORYLATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND SELECTIVE INTERACTION OF THE 5'-TRIPHOSPHATE WITH HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) : 8333 - 8337

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