SYNTHESIS OF 3'-FUNCTIONALIZED OLIGONUCLEOTIDES ON A SINGLE SOLID SUPPORT

被引：14

作者：

HOVINEN, J ^{[1
]}

GUZAEV, A ^{[1
]}

AZHAYEV, A ^{[1
]}

LONNBERG, H ^{[1
]}

机构：

[1] UNIV TURKU,DEPT CHEM,SF-20500 TURKU,FINLAND

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)61482-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oligodeoxyribonucleotides tethered with an amino-, carboxy-, amidocarbonyl-, or mercaptoalkyl spacer arm at 3'-terminus were obtained by assembling the chains on a modified aminoalkyl-CPG (1) and releasing them with appropriate reagents.

引用

页码：8169 / 8172

页数：4

共 23 条

[11] Guzaev A P, 1991, Nucleic Acids Symp Ser, P236
[12] THE SYNTHESIS OF POLYAMIDE OLIGONUCLEOTIDE CONJUGATE MOLECULES
HARALAMBIDIS, J
DUNCAN, L
ANGUS, K
TREGEAR, GW
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (03) : 493 - 499
[13] 3'-MODIFIED ANTISENSE OLIGODEOXYRIBONUCLEOTIDES COMPLEMENTARY TO CAMODULIN MESSENGER-RNA ALTER BEHAVIORAL-RESPONSES IN PARAMECIUM
HINRICHSEN, RD
FRAGA, D
REED, MW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (18) : 8601 - 8605
[14] A NEW METHOD TO PREPARE 3'-MODIFIED OLIGONUCLEOTIDES
HOVINEN, J
GOUZAEV, AP
AZHAYEV, AV
LONNBERG, H
[J]. TETRAHEDRON LETTERS, 1993, 34 (32) : 5163 - 5166
[15] AUTOMATED INCORPORATION OF POLYETHYLENE-GLYCOL INTO SYNTHETIC OLIGONUCLEOTIDES
JASCHKE, A
FURSTE, JP
CECH, D
ERDMANN, VA
[J]. TETRAHEDRON LETTERS, 1993, 34 (02) : 301 - 304
[16] SYNTHESIS AND PHYSICAL-PROPERTIES OF ANTI-HIV ANTISENSE OLIGONUCLEOTIDES BEARING TERMINAL LIPOPHILIC GROUPS
MACKELLAR, C
GRAHAM, D
WILL, DW
BURGESS, S
BROWN, T
[J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (13) : 3411 - 3417
[17] MILLER PS, 1991, OLIGONUCLEOTIDES ANA, P137
[18] OLIGONUCLEOTIDE LABELING METHODS .3. DIRECT LABELING OF OLIGONUCLEOTIDES EMPLOYING A NOVEL, NONNUCLEOSIDIC, 2-AMINOBUTYL-1,3-PROPANEDIOL BACKBONE
NELSON, PS
KENT, M
MUTHINI, S
[J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (23) : 6253 - 6259
[19] BIFUNCTIONAL OLIGONUCLEOTIDE PROBES SYNTHESIZED USING A NOVEL CPG SUPPORT ARE ABLE TO DETECT SINGLE BASE PAIR MUTATIONS
NELSON, PS
FRYE, RA
LIU, E
[J]. NUCLEIC ACIDS RESEARCH, 1989, 17 (18) : 7187 - 7194
[20] NYLAS A, 1993, BIOORG MED CHEM LETT, V3, P1371

← 1 2 3 →