THE GENE ENCODING MYELOID ALPHA-3-FUCOSYLTRANSFERASE(FUT4) IS LOCATED BETWEEN D11S388 AND D11S919 ON 11Q21

被引：26

作者：

REGUIGNE, I

JAMES, MR

RICHARD, CW

MOLLICONE, R

SEAWRIGHT, A

LOWE, JB

ORIOL, R

COUILLIN, P

机构：

[1] INSERM,U358,PARIS,FRANCE

[2] CEPH,PARIS,FRANCE

[3] UNIV PITTSBURGH,DEPT PSYCHIAT,PITTSBURGH,PA

[4] UNIV PITTSBURGH,DEPT HUMAN GENET,PITTSBURGH,PA

[5] WESTERN GEN HOSP,MRC,HUMAN GENET UNIT,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

[6] HOWARD HUGHES MED INST,ANN ARBOR,MI

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 66卷 / 02期

关键词：

D O I：

10.1159/000133677

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The last step in the biosynthesis of Le(x) antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different alpha-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid alpha-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.

引用

页码：104 / 106

页数：3

共 20 条

[11] 5 SPECIFICITY PATTERNS OF (1-]3)-ALPHA-L-FUCOSYL-TRANSFERASE ACTIVITY DEFINED BY USE OF SYNTHETIC OLIGOSACCHARIDE ACCEPTORS - DIFFERENTIAL EXPRESSION OF THE ENZYMES DURING HUMAN EMBRYONIC-DEVELOPMENT AND IN ADULT TISSUES [J].