ENANTIOSELECTIVE CATALYTIC ADDITION OF FUNCTIONALIZED DIALKYLZINC COMPOUNDS TO BETA-STANNYLATED ALDEHYDES - A CONVENIENT PREPARATION OF CHIRAL BETA-FUNCTIONALIZED AND GAMMA-FUNCTIONALIZED SECONDARY ALCOHOLS

被引：44

作者：

BRIEDEN, W ^{[1
]}

OSTWALD, R ^{[1
]}

KNOCHEL, P ^{[1
]}

机构：

[1] UNIV MARBURG,FACHBEREICH CHEM,HANS MEERWEIN STR,W-3550 MARBURG,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 04期

关键词：

D O I：

10.1002/anie.199305821

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High enantioselectivity is found in the Ti‐catalyzed addition of dialkylzinc compounds [R1(CH2)n]2Zn to the β‐stannylaldehydes 1 and 2 to give the polyfunctionalized products 3 and 4, respectively. Examples of (CH2)nR1: ethyl, octyl, (CH2)4Cl. R = Me, Bu. (Figure Presented.) Copyright © 1993 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：582 / 584

页数：3

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