IMIPRAMINE DEMETHYLATION AND HYDROXYLATION - IMPACT OF THE SPARTEINE OXIDATION PHENOTYPE

被引：109

作者：

BROSEN, K

OTTON, SV

GRAM, LF

机构：

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 1986年 / 40卷 / 05期

关键词：

D O I：

10.1038/clpt.1986.221

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：543 / 549

页数：7

相关论文

共 28 条

[1] THE DEBRISOQUINE HYDROXYLATION TEST PREDICTS STEADY-STATE PLASMA-LEVELS OF DESIPRAMINE
BERTILSSON, L
ABERGWISTEDT, A
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 15 (03) : 388 - 390
[2] BROSEN K, 1985, ACTA PHARMACOL TOX, V57, P357
[3] SPARTEINE OXIDATION POLYMORPHISM - A FAMILY STUDY
BROSEN, K
OTTON, SV
GRAM, LF
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 21 (06) : 661 - 667
[4] STEADY-STATE LEVELS OF IMIPRAMINE AND ITS METABOLITES - SIGNIFICANCE OF DOSE-DEPENDENT KINETICS
BROSEN, K
GRAM, LF
KLYSNER, R
BECH, P
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 30 (01) : 43 - 49
[5] BROSEN K, 1986, EUR J CLIN PHARM, V30
[6] BROSEN K, 1985, UNPUB
[7] CHARACTERIZATION OF A HUMAN-LIVER CYTOCHROME-P-450 INVOLVED IN THE OXIDATION OF DEBRISOQUINE AND OTHER DRUGS BY USING ANTIBODIES RAISED TO THE ANALOGOUS RAT ENZYME
DISTLERATH, LM
GUENGERICH, FP
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23): : 7348 - 7352
[8] INTER-ETHNIC DIFFERENCE IN SPARTEINE OXIDATION AMONG GHANAIANS AND GERMANS
EICHELBAUM, M
WOOLHOUSE, NM
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 28 (01) : 79 - 83
[9] THE GENETIC-CONTROL OF SPARTEINE AND DEBRISOQUINE METABOLISM IN MAN WITH NEW METHODS OF ANALYZING BIMODAL DISTRIBUTIONS
EVANS, DAP
HARMER, D
DOWNHAM, DY
WHIBLEY, EJ
IDLE, JR
RITCHIE, J
SMITH, RL
[J]. JOURNAL OF MEDICAL GENETICS, 1983, 20 (05) : 321 - 329
[10] GLASSMAN AH, 1977, ARCH GEN PSYCHIAT, V34, P197