SOLID-STATE INTERACTION OF STEROIDS WITH CALIXARENES .1. A PRELIMINARY FTIR AND DSC STUDY ON 4-EN-3-KETO-STEROIDS

被引：12

作者：

PARINI, C ^{[1
]}

COLOMBI, S ^{[1
]}

CASNATI, A ^{[1
]}

机构：

[1] UNIV PARMA,DIPARTIMENTO CHIM ORGAN & IND,I-43100 PARMA,ITALY

来源：

JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY | 1994年 / 18卷 / 04期

关键词：

STEROIDS; CALIXARENES; INCLUSION COMPLEXES; FTIR; DSC;

D O I：

10.1007/BF00707383

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Both DSC and FTIR studies indicate that co-grinding and co-precipitation cause steroids to interact with calixarenes. This interaction leads to breaking of the crystal lattice of the steroids, dispersion of the steroidal carbonyls in a hydrophobic environment and formation of hydrogen bonds between steroidal and calixarene hydroxyls. This interaction seems to be specific, depending on the structure of the calixarene and of the steroid involved. It is reasonable to assume that inclusion complexes are formed.

引用

页码：341 / 351

页数：11

共 19 条

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