EARLY POSTIMPLANTATION EMBRYO LETHALITY DUE TO DNA REARRANGEMENTS IN A TRANSGENIC MOUSE STRAIN

被引：103

作者：

COVARRUBIAS, L ^{[1
]}

NISHIDA, Y ^{[1
]}

MINTZ, B ^{[1
]}

机构：

[1] FOX CHASE CANC CTR,INST CANC RES,PHILADELPHIA,PA 19111

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 16期

关键词：

D O I：

10.1073/pnas.83.16.6020

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6020 / 6024

页数：5

共 31 条

[21] EMBRYONIC LETHAL MUTATION IN MICE INDUCED BY RETROVIRUS INSERTION INTO THE ALPHA-1(I) COLLAGEN GENE [J].

SCHNIEKE, A ;

HARBERS, K ;

JAENISCH, R .

NATURE, 1983, 304 (5924) :315-320

[22] DETECTION OF SPECIFIC SEQUENCES AMONG DNA FRAGMENTS SEPARATED BY GEL-ELECTROPHORESIS [J].

SOUTHERN, EM .

JOURNAL OF MOLECULAR BIOLOGY, 1975, 98 (03) :503-+

[23] CLONING OF V-REGION FRAGMENTS FROM MOUSE-LIVER DNA AND LOCALIZATION OF REPETITIVE DNA-SEQUENCES IN THE VICINITY OF IMMUNOGLOBULIN GENE SEGMENTS [J].

STEINMETZ, M ;

HOCHTL, J ;

SCHNELL, H ;

GEBHARD, W ;

ZACHAU, HG .

NUCLEIC ACIDS RESEARCH, 1980, 8 (08) :1721-1729

[24] RETROVIRUSES AS MUTAGENS - INSERTION AND EXCISION OF A NONTRANSFORMING PROVIRUS ALTER EXPRESSION OF A RESIDENT TRANSFORMING PROVIRUS [J].

VARMUS, HE ;

QUINTRELL, N ;

ORTIZ, S .

CELL, 1981, 25 (01) :23-36

[25] PRENATAL LETHALITIES IN MICE HOMOZYGOUS FOR HUMAN GROWTH-HORMONE GENE-SEQUENCES INTEGRATED IN THE GERM LINE [J].

WAGNER, EF ;

COVARRUBIAS, L ;

STEWART, TA ;

MINTZ, B .

CELL, 1983, 35 (03) :647-655

[26] THE HUMAN BETA-GLOBIN GENE AND A FUNCTIONAL VIRAL THYMIDINE KINASE GENE IN DEVELOPING MICE [J].

WAGNER, EF ;

STEWART, TA ;

MINTZ, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (08) :5016-5020

[27] EFFICIENT TRANSFER OF LARGE DNA FRAGMENTS FROM AGAROSE GELS TO DIAZOBENZYLOXYMETHYL-PAPER AND RAPID HYBRIDIZATION BY USING DEXTRAN SULFATE [J].

WAHL, GM ;

STERN, M ;

STARK, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (08) :3683-3687

[28] EFFECT OF CHROMOSOMAL POSITION ON AMPLIFICATION OF TRANSFECTED GENES IN ANIMAL-CELLS [J].

WAHL, GM ;

DESAINTVINCENT, BR ;

DEROSE, ML .

NATURE, 1984, 307 (5951) :516-520

[29] AN INHERITED LIMB DEFORMITY CREATED BY INSERTIONAL MUTAGENESIS IN A TRANSGENIC MOUSE [J].

WOYCHIK, RP ;

STEWART, TA ;

DAVIS, LG ;

DEUSTACHIO, P ;

LEDER, P .

NATURE, 1985, 318 (6041) :36-40

[30] DELETION OF IMMUNOGLOBULIN HEAVY-CHAIN GENES ACCOMPANIES THE CLASS SWITCH REARRANGEMENT [J].

YAOITA, Y ;

HONJO, T .

BIOMEDICAL RESEARCH-TOKYO, 1980, 1 (02) :164-175

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