ENDOTOXIC-SHOCK .1. A REVIEW OF CAUSES

被引：41

作者：

HARDIE, EM

KRUSEELLIOTT, K

机构：

[1] Departments of Companion Animal and Special Species Medicine, North Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina

[2] North Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina

来源：

JOURNAL OF VETERINARY INTERNAL MEDICINE | 1990年 / 4卷 / 05期

关键词：

D O I：

10.1111/j.1939-1676.1990.tb03119.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Endotoxic shock is a complex phenomenon resulting from systemic release of inflammatory mediators. Endotoxin interacts with inflammatory cells, platelets, and vascular endothelium. Cytokines, such as tumor necrosis factor and interleukins, and lipid mediators (platelet activating factor, thromboxane, prostacylin, leukotrienes) are released. These primary mediators act synergistically to cause many of the harmful effects associated with endotoxemia. Multiple secondary mediators are released in response to the primary mediators, compounding the damage. The end result is the species‐specific clinical syndrome recognized as endotoxemia. © 1990 American College of Veterinary Internal Medicine

引用

页码：258 / 266

页数：9

共 96 条

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